124841-84-5Relevant academic research and scientific papers
Increasing permeability of phospholipid bilayer membranes to alanine with synthetic α-aminophosphonate carriers
Danila, Delia C.,Wang, Xinyan,Hubble, Heather,Antipin, Igor S.,Pinkhassik, Eugene
, p. 2320 - 2323 (2008/09/20)
A series of aminophosphonates was synthesized, and their ability to carry alanine, a model hydrophilic molecule, across phospholipid bilayer membranes was evaluated. Aminophosphonates facilitate the membrane transport at moderate rates, which make them a suitable platform for the design of carriers for continuous drug release devices.
SYNTHESIS AND ACYLATION REACTIONS OF (1-AMINOCYCLOHEXYL)PHOSPHONATES
Yusupov, M. M.,Razhabov, A.,Iskandarov, R. S.,Abdusamatov, A. A.
, p. 461 - 466 (2007/10/02)
New dialkyl (1-aminocyclohexyl)phosphonates were synthesized, and their acylation was studied.It was found that N-acylated (1-aminocyclohexyl)phosphonates are unstable compounds and are split at the phosphorus-carbon bond into a phosphite and an enamide.
