124845-21-2

Basic information

• Product Name: 1H-Pyrazole-4-carboxamide,1,3-dimethyl-(9CI)
• Synonyms: 1H-Pyrazole-4-carboxamide,1,3-dimethyl-(9CI);1,3-diMethyl-1H-pyrazole-4-carboxaMide
• CAS NO: 124845-21-2
• Molecular Formula: C₆H₉N₃O
• Molecular Weight: 139.15516
• Product Categories: AMIDE
• Mol File: 124845-21-2.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Pyrazole-4-carboxamide,1,3-dimethyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole-4-carboxamide,1,3-dimethyl-(9CI)(124845-21-2)
• EPA Substance Registry System: 1H-Pyrazole-4-carboxamide,1,3-dimethyl-(9CI)(124845-21-2)

Safety Data

• Hazardous Substances Data: 124845-21-2(Hazardous Substances Data)

Usage

Type of compound

pyrazole derivative

Characterized by

a pyrazole ring, a carboxamide group, and two methyl groups at the 1 and 3 positions

Potential applications

medicinal chemistry (pharmaceutical drugs and agrochemicals)

Possible biological activities

antimicrobial, antifungal, and anticancer agent

Research interests

physicochemical properties and synthetic pathways in organic chemistry and drug discovery.

Upstream product

• 113100-61-1 1,3-dimethyl-1H-pyrazole-4-carboxylic acid chloride 
• 85290-76-2 1-methyl-3-methyl-1H-pyrazole-4-carboxylic acid ethyl ester 
• 49836-24-0 (E)-2-(ethoxymethylene)-3-oxobutanoic acid ethyl ester 
• 78703-53-4 1,3-dimethyl-1H-pyrazole-4-carboxylic acid 

Downstream Products

• 133053-61-9 1,3-Dimethyl-5-(3-phenoxyprop-1-ynyl)pyrazole-4-carbonamide 
• 133053-64-2 1,3-Dimethyl-6-phenoxymethyl-1,5-dihydro-pyrazolo[4,3-c]pyridin-4-one 

Relevant articles and documents

Acyl urea compound containing 1,3-dimethyl-1H-pyrazole structure and preparation method and application thereof

The invention discloses an acyl urea compound containing a 1,3-dimethyl-1H-pyrazole structure and a preparation method and application thereof. The preparation method comprises the following steps: firstly using ethyl acetoacetate, triethyl orthoformate and methylhydrazine as raw materials to synthesize 1,3-dimethyl-1H-pyrazole-4-formic acid, performing the amidation to obtain 1,3-dimethyl-1H-pyrazole-4-formamide, and reacting with oxalyl chloride and substituted anilines to obtain a final product (I). The raw materials are simple and are easily obtained, the preparation method is simple, the aftertreatment is convenient, and the product yield is high. The compound has the antifungal activity, and has the good sterilizing effect in allusion to sclerotinia sclerotiorum, rhizoctonia solani, Cercospora arachidicola Hori, Macrophoma kawatsukai, and alternaria solani especially. The foundation is provided for new pesticide research and development.