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(4S)-4-[4-cyano-2-(methylsulfanyl)phenyl]-6-methyl-2-oxo-1-[3-(trifluoromethyl)-phenyl]-1,2,3,4-tetrahydropyrimidine-5-carboxamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1248520-97-9

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1248520-97-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1248520-97-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,8,5,2 and 0 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1248520-97:
(9*1)+(8*2)+(7*4)+(6*8)+(5*5)+(4*2)+(3*0)+(2*9)+(1*7)=159
159 % 10 = 9
So 1248520-97-9 is a valid CAS Registry Number.

1248520-97-9Relevant academic research and scientific papers

Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases

Vonnussbaum, Franz,Li, Volkhart M.-J.,Allerheiligen, Swen,Anlauf, Sonja,B?rfacker, Lars,Bechem, Martin,Delbeck, Martina,Fitzgerald, Mary F.,Gerisch, Michael,Gielen-Haertwig, Heike,Haning, Helmut,Karthaus, Dagmar,Lang, Dieter,Lustig, Klemens,Meibom, Daniel,Mittendorf, Joachim,Rosentreter, Ulrich,Sch?fer, Martina,Sch?fer, Stefan,Schamberger, Jens,Telan, Leila A.,Tersteegen, Adrian

, p. 1163 - 1173 (2015/07/07)

Human neutrophil elastase (HNE) is a key protease for matrix degradation. High HNE activity is observed in inflammatory diseases. Accordingly, HNE is a potential target for the treatment of pulmonary diseases such as chronic obstructive pulmonary disease

SULFONIC AMIDE AND SULFOXIMINE-SUBSTTTUTED DIARYL-DIHYDROPYRIMIDINONES AND USAGE THEREOF

-

, (2012/04/23)

The present application relates to novel sulfonamidw- or sulfoximine-substituted 1,4-diaryldihydropyrimidin-2-one derivatives, to processes for their preparation, to their use alone or in combination for the treatment and/or prevention of diseases and als

4-(4-CYANO-2-THIOARYL)DIHYDRO PYRIMIDINONES AND THEIR USE

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, (2011/02/26)

The present invention relates to novel 4-(4-cyano-2-thioaryl) dihydropyrimidin-2-one derivatives, to processes for their preparation, to their use alone or in combination for the treatment and/or prevention of diseases and also to their use for preparing

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