1248592-64-4Relevant academic research and scientific papers
Synthesis of MUC1-lipopeptide chimeras
Wilkinson, Brendan L.,Malins, Lara R.,Chun, Candy K. Y.,Payne, Richard J.
, p. 6249 - 6251 (2010)
An efficient method for the convergent assembly of MUC1-lipopeptide vaccine candidates is described. Chimeras consisting of MUC1 glycopeptides (bearing multiple copies of the TN and T tumour-associated carbohydrate antigens) tethered to the lipopeptide immunoadjuvant Pam3CysSer were synthesised in high yields using a fragment-based condensation strategy.
