124867-50-1

Basic information

• Product Name: 1-(hydroxymethyl)-5,7,8-trimethoxy-6-methyl-3,4-dihydro-1H-isoquinolin e-2-carbaldehyde
• Synonyms: 1-(hydroxymethyl)-5,7,8-trimethoxy-6-methyl-3,4-dihydro-1H-isoquinolin e-2-carbaldehyde
• CAS NO: 124867-50-1
• Molecular Formula: C₁₅H₂₁NO₅
• Molecular Weight: 295.33
• Mol File: 124867-50-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 489.4°C at 760 mmHg
• Flash Point: 249.8°C
• Appearance: /
• Density: 1.226g/cm³
• Vapor Pressure: 2.16E-10mmHg at 25°C
• Refractive Index: 1.576
• CAS DataBase Reference: 1-(hydroxymethyl)-5,7,8-trimethoxy-6-methyl-3,4-dihydro-1H-isoquinolin e-2-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(hydroxymethyl)-5,7,8-trimethoxy-6-methyl-3,4-dihydro-1H-isoquinolin e-2-carbaldehyde(124867-50-1)
• EPA Substance Registry System: 1-(hydroxymethyl)-5,7,8-trimethoxy-6-methyl-3,4-dihydro-1H-isoquinolin e-2-carbaldehyde(124867-50-1)

Safety Data

• Hazardous Substances Data: 124867-50-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H21NO5/c1-9-13(19-2)10-5-6-16(8-18)11(7-17)12(10)15(21-4)14(9)20-3/h8,11,17H,5-7H2,1-4H3

Upstream product

• 98498-42-1 1-Hydroxymethyl-6-methyl-5,7,8-trimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 109-94-4 formic acid ethyl ester 
• 124867-32-9 {Benzyl-[2-(2,4,5-trimethoxy-3-methyl-phenyl)-ethyl]-amino}-butoxy-acetic acid butyl ester 
• 110828-13-2 2,2-dimethoxy-N-(2,3,5-trimethoxy-4-methylbenzyl)-N-tosylethylamine 
• 110828-15-4 N-benzoyl-1-cyano-5,7,8-trimethoxy-6-methyl-1,2-dihydroisoquinoline 
• 110828-14-3 5,7,8-trimethoxy-6-methyl-N-tosyl-1,2-dihydroisoquinoline 
• 124867-44-3 Butyl 6-methyl-5,7,8-trimethoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylate 
• 124867-37-4 2-Benzyl-1-hydroxymethyl-6-metyl-5,7,8-trimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 94893-31-9 2,2-dimethoxy-N-(2,3,5-trimethoxy-4-methylbenzylidene)ethylamine 
• 110828-12-1 2,2-dimethoxy-N-(2,3,5-trimethoxy-4-methylbenzyl)ethylamine 
• 77515-78-7 1-Hydroxymethyl-6-methyl-5,7,8-trimethoxyisoquinoline 
• 85071-59-6 1-bromo-2,3,5-trimethoxy-4-methylbenzaldehyde 
• 113967-11-6 Butyl 2-benzyl-5,7,8-trimethoxy-6-methyl-1,2,3,4-tetrahydroisoquinoline-1-carboxylate 
• 113966-96-4 N-Benzyl-2-(2,4,5-trimethoxy-3-methylphenyl)ethylamine 

Downstream Products

• 97581-21-0 (N-formyl-7-methoxy-6-methyl-5,8-dioxo-1,2,3,4,5,8-hexahydro-1-isoquinolyl)methyl benzoate 
• 97581-09-4 (N-formyl-7-methoxy-6-methyl-5,8-dioxo-1,2,5,8-tetrahydro-1-isoquinolyl)methyl benzoate 
• 79664-57-6 (2-formyl-1,2,5,8-tetrahydro-7-methoxy-6-methyl-5,8-dioxo-1-isoquinolinyl)methyl (2Z)-2-methyl-2-butenoate 
• 128252-84-6 (N-formyl-5,7,8-trimethoxy-6-methyl-1,2,3,4-tetrahydro-1-isoquinolyl)methyl benzoate 

Relevant articles and documents

A facile synthesis of 1,2,3,4-tetrahydroisoquinolines through cyclization of O,N-acetals. II. Syntheses of isoquinolinequinone antibiotics

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Synthesis of isoquinolinequinone antibiotics from a marine sponge Reniera sp.

Synthesis of two isoquinolinequinone antibiotics, 7-methoxy-1,6-dimethyl-5,8-dihydroisoquinoline-5,8-dione and N-formyl-1,2-dihydrorenierone, isolated from a marine sponge Reniera sp., are described.