124887-55-4Relevant academic research and scientific papers
Total Synthesis of Sophorapterocarpan A, Maackiain, and Anhydropisatin: Application of a 1,3-Michael-Claisen Annulation to Aromatic Synthesis
Ozaki, Yutaka,Mochida, Keiko,Kim, Sang-Won
, p. 1219 - 1224 (2007/10/02)
A new synthetic route to the pterocarpans using a annulation is described. 1,3-Michael-Claisen condensation of α-methylene-γ-butyrolactones with α-sulphur-substituted ketones gives 6-membered rings which have been converted into the pterocarpan framework by aromatization.Sophorapterocarpan A, maackiain, and anhydropisatin have been prepared employing this new aromatic synthesis.
Aromatic Ring Formation by the 1,3-Michael-Claisen Annulation: Total Synthesis of Sophorapterocarpan A, Maackiain, and Anhydropisatin
Ozaki, Yutaka,Mochida, Keiko,Kim, Sang-Won
, p. 374 - 375 (2007/10/02)
The utility of the 1,3-Michael-Claisen annulation sequence in the synthesis of natural products has been demonstrated by the synthesis of sophorapterocarpan A (1), maackiain (2), and anhydropisatin (3).
