124901-17-3

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 52287-56-6 1-(p-tolyl)-2-nitropropene 
• 145101-11-7 ethyl 4-methyl-1-methylsulfonyl-3-(p-tolyl)-2-pyrrolecarboxylate 
• 145101-15-1 (1-Methanesulfonyl-4-methyl-3-p-tolyl-1H-pyrrol-2-yl)-methanol 
• 124901-13-9 ethyl 4-methyl-3-(p-tolyl)-2-pyrrolecarboxylate 
• 145101-35-5 (4-Methyl-3-p-tolyl-1H-pyrrol-2-yl)-methanol 

Relevant academic research and scientific papers

Porphyrin synthesis from nitrocompounds

A new porphyrin synthesis starting from nitroalkenes or their equivalents is described. For example, octaethylporphyrin, coproporphyrin, porphyrin-1,2,3,4,5,6,7,8 octapropionic acid, and 2,7,12,17 tetraarylporphyrin are prepared in good yield from readily available materials such as 1-nitropropane, nitroethane, nitromethane, and aldehydes.

A New Synthesis of Porphyrins via Tetramerization of 2-(Hydroxymethyl)pyrroles

Acid catalyzed cyclization of 2-(hydroxymethyl)pyrroles with electron-donating substituents at the β-position gives a mixture of four isomers of porphyrins (type I-IV) in the homogeneous reaction.The isomerization during cyclization can be minimized in th