124957-57-9

Upstream product

• 124957-43-3 methyl (2E)-2-(acetoxymethyl)-3-(2-methoxyphenyl)prop-2-enoate 
• 125001-97-0 2-[(2-Methoxy-phenyl)-phenylcarbamoyloxy-methyl]-acrylic acid methyl ester 
• 115240-90-9 methyl 2-(hydroxy(2-methoxyphenyl)methyl)acrylate 
• 124957-37-5 2-[Acetoxy-(2-methoxy-phenyl)-methyl]-acrylic acid methyl ester 
• 139413-77-7 (Z)-2-Bromomethyl-3-(2-methoxy-phenyl)-acrylic acid methyl ester 
• 62-53-3 aniline 
• 135-02-4 ortho-anisaldehyde 

Relevant academic research and scientific papers

A simple and direct synthesis of 3-methylene-1, 4-diarylazetidin-2-ones and (E)-3-arylidene-1-phenylazetidin-2-ones using baylis-hillman derivatives

Herein we describe a direct method, promoted by potassium tert-butoxide (KOtBu), for the synthesis of highly substituted α-methylene β-lactams and α-arylidene β-lactams from the amino ester intermediates derived from the acetates and bromo derivatives of

Preparation d'amines allyliques a partir d'acyloxy-3 methylene-2 propionates de methyle substitues en 3 par un groupement aromatique ou heteroaromatique

The reaction of substituted methyl 3-acetoxy 2-methylene propionates 2 with aliphatic amines gives allylic amines.The E configuration is predominant.The reaction of esters 2 with aniline does not give allylic amines.These amines are prepared by rearrangement of the carbamates which are obtained by the reaction of phenyl isocyanate with methyl 3-hydroxy 2-methylene propionates 1.The primary allylic amines are prepared through the reduction of azides 11.