124985-48-4Relevant academic research and scientific papers
Suppression of alkene isomerisation in products from intramolecular Heck reactions by addition of Tl(1) salts
Grigg,Loganathan,Santhakumar,Sridharan,Teasdale
, p. 687 - 690 (1991)
Palladium catalysed cyclisations creating products possessing spiro-, fused- and bridged-rings, and tetrasubstituted carbon centres as mixtures of double bond isomers are modified to give single products in the presence of Tl(1) salts.
THE SYNTHESIS OF SPIROCYCLIC COMPOUNDS BY REGIOSPECIFIC PALLADIUM CATALYSED CYCLISATION REACTIONS
Grigg, Ronald,Sridharan, Visuvanathar,Stevenson, Paul,Sukirthalingam, Sukanthini
, p. 3557 - 3568 (2007/10/02)
Enamides derived from o-iodobenzoic acid and Z-3-bromoacrylic acid undergo regiospecific palladium catalysed exo-trig cyclisation onto a proximate alkene to give spirocyclic products in good to excellent yield.Double bond isomerisation in the product is n
