124990-69-8Relevant academic research and scientific papers
INVESTIGATIONS IN THE FIELD OF DERIVATIVES OF ASYMMETRICALLY SUBSTITUTED myo-INOSITOL. XXXVI. SEPARATION OF DIASTEREOMERIC CARBOHYDRATE DERIVATIVES OF myo-INOSITOL BY THE HPLC METHOD
Runova, O. B.,Krylova, V. N.,Shastina, N. S.,Eremin, S. V.,Stepanov, A. E.,Shvets, V. I.
, p. 249 - 257 (2007/10/02)
The possibility has been shown of using the HPLC method for separating diastereomeric compounds of myo-inositol obtained under the conditions of the transesterification of racemic myo-inositol derivatives with D-mannose (ethyl orthoacetate).The optically active myo-inositol derivatives obtained can be used for the synthesis of myo-inositol phosphates with various structures.
TOTAL SYNTHESES OF CHIRAL sn-myo-INOSITOL-1,4,5-TRISPHOSPHATE AND ITS ENANTIOMER.
Stepanov, Alexander E.,Runova, Olga B.,Schlewer, Gilbert,Spiess, Bernard,Shvets, Vitaly I.
, p. 5125 - 5128 (2007/10/02)
sn-myo-Inositol-1,4,5-trisphosphate (Ins(1,4,5)P3) and its enantiomers are prepared by synthesis of suitably protected myo-inositols, separation of enantiomers via the formation of D-mannose diastereomeric derivatives and selective phosphorylations.
