1250258-01-5Relevant academic research and scientific papers
Suzuki-Miyaura reactions of N-protected tribromopyrazoles. Efficient and site-selective synthesis of 3,4,5-triaryl-pyrazoles, 3,5-diaryl-4-bromopyrazoles and 5-aryl-3,4-dibromopyrazoles
Khera, Rasheed Ahmad,Ali, Asad,Rafique, Hummera,Hussain, Munawar,Tatar, Jovana,Saeed, Aamer,Villinger, Alexander,Langer, Peter
experimental part, p. 5244 - 5253 (2011/08/04)
Suzuki-Miyaura reactions of N-protected tribromopyrazoles were studied. The reactions proceed with excellent site-selectivity. The first attack occurs at position 5, while the second and third attack occur at positions 3 and 4, respectively. A variety of 3,4,5-triaryl-pyrazoles, 3,5-diaryl-4-bromopyrazoles, and 5-aryl-3,4-dibromopyrazoles were efficiently prepared. The products are not readily available by other methods.
Synthesis of Arylated Pyrazoles by site-selective suzuki-miyaura reactions of tribromopyrazoles
Khera, Rasheed Ahmad,Ali, Asad,Hussain, Munawar,Tatar, Jovana,Villinger, Alexander,Langer, Peter
experimental part, p. 1923 - 1926 (2010/10/01)
The first Suzuki-Miyaura reactions of N-protected tribromopyrazoles are reported. Their reaction with three, two, or one equivalents of arylboronic acids afforded 3,4,5-triarylpyrazoles, 3,5-diaryl-4-bromopyrazoles, or 5-aryl-3,4-dibromopyrazoles, respect
