1250263-06-9Relevant academic research and scientific papers
Development of 2-pyrrolidinyl-N-methyl pyrimidones as potent and orally bioavailable HIV integrase inhibitors
Ferrara, Marco,Fiore, Fabrizio,Summa, Vincenzo,Gardelli, Cristina
scheme or table, p. 5031 - 5034 (2010/10/01)
A series of 2-pyrrolidinyl-N-methyl pyrimidones HIV integrase inhibitors has been explored leading to the identification of derivative 13, which showed high activity at inhibiting viral replication in cell culture, favorable pharmacokinetic profile in two
