125037-07-2

Upstream product

• 2062-98-8 perfluoro(2-propoxypropionyl) fluoride 
• 13252-13-6 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid 
• 13252-13-6 (+)-2-(heptafluoropropoxy)perfluoropropionic acid 

Downstream Products

• 112586-75-1 (3,4,4,4-Tetrafluoro-3-heptafluoropropyloxy-but-1-ynyloxy)-benzene 
• 112586-78-4 1-Chloro-4-(3,4,4,4-tetrafluoro-3-heptafluoropropyloxy-but-1-ynyloxy)-benzene 
• 13252-13-6 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid 

Relevant academic research and scientific papers

Preparation method of fluorine-containing carboxylic acid

The invention discloses a preparation method of fluorine-containing carboxylic acid. The method comprises the following steps: reacting fluorine-containing carboxylate used as a raw material with an acylating chlorination reagent to obtain a corresponding mixture of fluorine-containing acyl chloride and fluorine-containing anhydride, and hydrolyzing and drying the mixture of fluorine-containing acyl chloride and fluorine-containing anhydride to obtain high-purity fluorine-containing carboxylic acid. The method provided by the invention is suitable for post-treatment of fluorine-containing carboxylic acid prepared by a fluorine-containing olefin (monoolefine, diene, cycloolefin and the like) oxidation method, replaces the traditional strong acid acidification and ether continuous extractionprocess, and is simpler, more convenient and more applicable; and the method can also be used for recovering and purifying a fluorine-containing carboxylate emulsifier. The purity of the fluorine-containing carboxylic acid prepared by the method can reach 98% or above.

Synthesis of novel perfluoroalkyl ether derivatives

A series of novel fluoroether-containing monomers has been designed and prepared based on the commercially available perfluoroalkyl ether acid fluoride. Treating acid fluoride with allyl alcohol, 2-hydroxyethyl methacrylate or N-allylmethylamine allowed for the direct formation of corresponding vinyl-containing fluorinated monomers. High yields of the fluorinated epoxy monomers could be obtained from acid chloride with glycidol; meanwhile, fluorinated diol was prepared from diethanolamine or 3-amino-1,2-propanediol. Moreover, fluorinated monoamine, fluorinated monoalcohol and fluorinated dichloride were also obtained. Most of these fluorinated monomers were liquid at room temperature and exhibited good solubility in common organic solvents.

OPTICALLY ACTIVE PERFLUORO-2-PROPOXYPROPIONIC ACID: A NEW CHIRAL REAGENT FOR 19F NMR STUDY

Perfluoro-2-propoxypropionic acid, which was prepared by the anionic dimerization of hexafluoro-1,2-epoxypropane, was optically resolved via diastereomeric salt formation with chiral amines.The optically pure (+) and (-) perfluoro-2-propoxypropionic acids thus obtained were found to be a convenient chiral reagent for determining enantiomeric compositions of α-amino acids by means of 19F nmr analysis.