125041-90-9

Upstream product

• 99-91-2 para-chloroacetophenone 
• 6287-38-3 3,4-dichlorobenzaldehyde 

Downstream Products

• 1217356-22-3 5-(3,4-dichlorophenyl)-7-(4-chlorophenyl)-1,3-dimethylpyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 
• 1499228-15-7 N-[4-(4-chlorophenyl)-6-(3,4-dichlorophenyl)pyrimidin-2-yl]benzenesulphonamide 
• 1354916-00-9 4-(4-chlorophenyl)-6-(3,4-dichlorophenyl)pyrimidin-2-amine 
• 170939-36-3 (4-Chloro-phenyl)-[4-(3,4-dichloro-phenyl)-1H-pyrrol-3-yl]-methanone 

Relevant academic research and scientific papers

Chalcones as promising pesticidal agents against diamondback moth (Plutella xylostella): Microwave-assisted synthesis and structure-activity relationship

A series of chalcones (A-CH=CH-CO-B) were synthesized under microwave irradiation, and for the first time their pesticidal activity against diamondback moth (Plutella xylostella) was evaluated to identify the promising lead structures. The structure-activity relationship (SAR) analysis revealed that electron-withdrawing substituents on ring A of chalcone provided good pesticidal agents, whereas, ring B can bear either electron-withdrawing or electron-releasing substituents. Moreover, compound 22 having para-Cl substitution on ring A as well on ring B showed maximum activity with LC 50 value of 170.24 μg mL-1. Springer Science+Business Media, LLC 2011.

COMPOSITION FOR DESTRUCTION OF MICROALGAE OR SPHAEROCARPUS

The present disclosure relates to a composition for the destruction of microalgae or mosses. The composition for the destruction of microalgae or mosses may suppress the growth and proliferation of microalgae when treated in moss cultivation facilities, marine microalgae cultivation facilities, areas in which green or red tide is occurring, or areas in which green or red tide is expected to occur, thereby preventing damage caused by the green or red tide.

Synthesis and algicidal activity of new dichlorobenzylamine derivatives against harmful red tides

In the present study, we synthesized 65 dichlorobenzylamine derivatives and investigated their algicidal activity against harmful red tides. The 3,4-dichlorobenzylamine derivatives showed relatively high activity against Cochlodinium polykrikoides, Heterosigma akashiwo, Chattonella marina, and Heterocapsa circularisquama, and the synthesized compounds 27, 28, 33, 34, 35, and 36 showed the highest algicidal activity after 24 h at 0.1 ~ 1.0 μM LC50 against the four harmful algae species. To verify the safety of the compounds, acute ecotoxicology tests using the water flea (Daphnia magna) and zebrafish (Danio rerio) were conducted, and the tests confirmed that compounds 33 and 34 were not harmful because the target organisms showed high survival rates at 15 μM. The results indicate that compounds 33 and 34 are suitable substances for use in controlling harmful algae species.

Synthesis, characterization of 4,6-disubstituted aminopyrimidines and their sulphonamide derivatives as anti-Amoebic agents

The present study describes the synthesis and anti-Amoebic activity of 4,6-disubstituted aminopyrimidines (1b-10b) and their sulphonamide derivatives (1-20). All the desired compounds were characterized by spectral data and their purity was confirmed by e

Hepatocyte growth factor pathway activators in chronic obstructive pulmonary disease

Methods are provided for treating chronic obstructive pulmonary diseases such as emphysema using compounds that activate the signaling pathways of hepatocyte growth factor.