125067-75-6

Basic information

• Product Name: 3-(3-FLUOROPHENYL)PYRROLIDINE
• Synonyms: 3-(3-FLUOROPHENYL)PYRROLIDINE;Pyrrolidine, 3-(3-fluorophenyl)-
• CAS NO: 125067-75-6
• Molecular Formula: C10H12FN
• Molecular Weight: 165.2073832
• Mol File: 125067-75-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 238.5 °C at 760 mmHg
• Flash Point: 98 °C
• Appearance: white to beige crystals or crystalline powder
• Density: 1.078 g/cm³
• Vapor Pressure: 0.0423mmHg at 25°C
• Refractive Index: 1.515
• Storage Temp.: 2-8°C
• PKA: 9.96±0.10(Predicted)
• CAS DataBase Reference: 3-(3-FLUOROPHENYL)PYRROLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-FLUOROPHENYL)PYRROLIDINE(125067-75-6)
• EPA Substance Registry System: 3-(3-FLUOROPHENYL)PYRROLIDINE(125067-75-6)

Safety Data

• Hazardous Substances Data: 125067-75-6(Hazardous Substances Data)

Usage

General Description

3-(3-Fluorophenyl)pyrrolidine is a chemical compound with the molecular formula C10H12FN. It is a pyrrolidine derivative with a fluorine-substituted phenyl group attached to the third position of the pyrrolidine ring. 3-(3-FLUOROPHENYL)PYRROLIDINE has a variety of potential applications, including as a building block in organic synthesis, as a research tool in the development of new pharmaceuticals, and in the study of the structure-activity relationships of drugs. Its unique structure and properties make it an interesting and versatile chemical for use in a range of applications.

InChI:InChI=1/C10H12FN/c11-10-3-1-2-8(6-10)9-4-5-12-7-9/h1-3,6,9,12H,4-5,7H2

Upstream product

• 60050-32-0 3-(3-fluoro-phenyl)-pyrrolidine-2,5-dione 

Relevant articles and documents

Synthesis of 3-(3-aryl-pyrrolidin-1-yl)-5-aryl-1,2,4-triazines that have antibacterial activity and also inhibit inorganic pyrophosphatase

Inorganic pyrophosphatases are potential targets for the development of novel antibacterial agents. A pyrophosphatase-coupled high-throughput screening assay intended to detect o-succinyl benzoic acid coenzyme A (OSB CoA) synthetase inhibitors led to the unexpected discovery of a new series of novel inorganic pyrophosphatase inhibitors. Lead optimization studies resulted in a series of 3-(3-aryl-pyrrolidin-1-yl)-5-aryl-1,2,4-triazine derivatives that were prepared by an efficient synthetic pathway. One of the tetracyclic triazine analogues 22h displayed promising antibiotic activity against a wide variety of drug-resistant Staphylococcus aureus strains, as well as activity versus Mycobacterium tuberculosis and Bacillus anthracis, at a concentration that was not cytotoxic to mammalian cells.