Cas 125075-86-7,(2S,4S,5S)-5-{N-[2(R)-(1-naphthylmethyl)-3-(morpholinocarbonyl)propionyl]-3-(4-thiazolyl)-L-alanyl}amino-6-cyclohexyl-4-hydroxy-2-(1-hydroxy-1-methylethyl)-N-methylhexanamide

125075-86-7

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Product Name: (2S,4S,5S)-5-{N-[2(R)-(1-naphthylmethyl)-3-(morpholinocarbonyl)propionyl]-3-(4-thiazolyl)-L-alanyl}amino-6-cyclohexyl-4-hydroxy-2-(1-hydroxy-1-methylethyl)-N-methylhexanamide
Synonyms: (2S,4S,5S)-5-{N-[2(R)-(1-naphthylmethyl)-3-(morpholinocarbonyl)propionyl]-3-(4-thiazolyl)-L-alanyl}amino-6-cyclohexyl-4-hydroxy-2-(1-hydroxy-1-methylethyl)-N-methylhexanamide
CAS NO:125075-86-7
Molecular Formula:
Molecular Weight: 763.999
EINECS: N/A
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Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
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Solubility: N/A
CAS DataBase Reference: (2S,4S,5S)-5-{N-[2(R)-(1-naphthylmethyl)-3-(morpholinocarbonyl)propionyl]-3-(4-thiazolyl)-L-alanyl}amino-6-cyclohexyl-4-hydroxy-2-(1-hydroxy-1-methylethyl)-N-methylhexanamide(CAS DataBase Reference)
NIST Chemistry Reference: (2S,4S,5S)-5-{N-[2(R)-(1-naphthylmethyl)-3-(morpholinocarbonyl)propionyl]-3-(4-thiazolyl)-L-alanyl}amino-6-cyclohexyl-4-hydroxy-2-(1-hydroxy-1-methylethyl)-N-methylhexanamide(125075-86-7)
EPA Substance Registry System: (2S,4S,5S)-5-{N-[2(R)-(1-naphthylmethyl)-3-(morpholinocarbonyl)propionyl]-3-(4-thiazolyl)-L-alanyl}amino-6-cyclohexyl-4-hydroxy-2-(1-hydroxy-1-methylethyl)-N-methylhexanamide(125075-86-7)

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HazardClass: N/A
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Hazardous Substances Data: 125075-86-7(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 125075-86-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,0,7 and 5 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 125075-86:
(8*1)+(7*2)+(6*5)+(5*0)+(4*7)+(3*5)+(2*8)+(1*6)=117
117 % 10 = 7
So 125075-86-7 is a valid CAS Registry Number.

125075-86-7Upstream product

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125075-86-7Relevant academic research and scientific papers

RENIN-INHIBITORY OLIGOPEPTIDES, THEIR PREPARATION AND USE

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, (2008/06/13)

Compounds of formula (I): STR1 A is a carbon-carbon bond or C 1-C 3 alkylene; B is imino group or C 1-C 2 alkylene; R 1 is C 1-C 4 alkyl, C 1-C 4 alkoxy, heterocyclic or optionally substituted amino; R 2 is optionally substituted phenyl or optionally substituted naphthyl; R 3 is thiazolyl, isoxazolyl or imidazolyl; R 4 is isopropyl or cyclohexyl; R 5 and R 6 are C. sub.1-C 4 alkyl, or, together with the carbon atom to which they are attached, C 3-C 7 cycloalkyl; R. sup.7 is hydrogen, optionally substituted C 1-C 6 alkyl group; and R 8 is hydrogen or C. sub.1-C 4 alkyl. These compounds have renin-inhibitory and, hence, hypotensive activities. The invention also provides a method for the treatment or prophylaxis of hypertension induced by failures in the renin-angiotensin system.

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