1250853-96-3

Upstream product

• 1247231-92-0 2-(4-chloro-3-fluorophenyl)-6-methylpyrimidin-4-one 
• 1190785-41-1 4-chloro-3-fluorobenzamidine 
• 110888-15-8 4-chloro-3-fluorobenzonitrile 

Downstream Products

• 504404-33-5 2-(4-chloro-3-fluorophenyl)-6-methyl-N-[2-(1-oxidopyridin-3-yl)ethyl]pyrimidin-4-amine 

Relevant academic research and scientific papers

Discovery and biological evaluation of novel 4-amino-2-phenylpyrimidine derivatives as potent and orally active GPR119 agonists

Novel 4-amino-2-phenylpyrimidine derivatives were synthesized and evaluated as GPR119 agonists. Optimization of the substituents on the phenyl ring at the 2-position and the amino group at the 4-position led to the identification of 3,4-dihalogenated and