125090-26-8

Basic information

• Product Name: 2-tritylamino-4-benzyloxycarbonyl-5-hydroxy-(2S,4R,5S)-heptanoic acid lactone
• Synonyms: 2-tritylamino-4-benzyloxycarbonyl-5-hydroxy-(2S,4R,5S)-heptanoic acid lactone
• CAS NO: 125090-26-8
• Molecular Weight: 519.64
• Mol File: 125090-26-8.mol

Chemical Properties

• CAS DataBase Reference: 2-tritylamino-4-benzyloxycarbonyl-5-hydroxy-(2S,4R,5S)-heptanoic acid lactone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-tritylamino-4-benzyloxycarbonyl-5-hydroxy-(2S,4R,5S)-heptanoic acid lactone(125090-26-8)
• EPA Substance Registry System: 2-tritylamino-4-benzyloxycarbonyl-5-hydroxy-(2S,4R,5S)-heptanoic acid lactone(125090-26-8)

Safety Data

• Hazardous Substances Data: 125090-26-8(Hazardous Substances Data)

Upstream product

• 73469-43-9 dibenzyl N-trityl-(S)-glutamate 
• 123-38-6 propionaldehyde 

Relevant articles and documents

SYNTHESIS OF NONPROTEINOGENIC AMINO ACIDS PART 2: PREPARATION OF A SYNTHETIC EQUIVALENT OF THE γ-ANION SYNTHON FOR ASYMMETRIC AMINO ACID SYNTHESIS

The synthesis of α-t-butyl γ-methyl N-trityl-(S)-glutamate (12) from (S)-glutamic acid (6) is described.Diester (12), on treatment with lithium isopropylcyclohexylamide followed by the addition of carbonyl compounds, reacts to give the γ-substituted glutamic acid derivatives (13a-i) with retention of optical purity at the α centre.