125136-88-1Relevant academic research and scientific papers
Enhanced Enantioselectivity of an Enzymatic Reaction by the Sulfur Functional Group. A Simple Preparation of Optically Active β-Hydroxy Nitriles Using a Lipase
Itoh, Toshiyuki,Takagi, Yumiko,Nishiyama, Shigenori
, p. 1521 - 1524 (2007/10/02)
The enantioselectivity of a lipase-catalyzed hydrolysis was improved by varying the acyl residue into the sulfur functional one, i.e. the β-(phenylthio)- or β-(methylthio)acetoxy group, from acetate or valerate to realize satisfactory resolution of β-hydr
Stereorecognition Enhancement by the Sulfur Functional Group in the Lipase Hydrolysis. An Efficient Synthesis of the Optically Active β-Hydroxy Nitriles
Itoh, Toshiyuki,Takagi, Yumiko
, p. 1505 - 1506 (2007/10/02)
β-phenylthio and β-methylthioacetoxy nitriles have been found to be good substrates for the kinetic resolution by lipase to give optically active β-hydroxy nitriles with high enantioselectivity.
