125155-33-1

Upstream product

• 3317-61-1 5,5-Dimethyl-1-pyrroline N-oxide 
• 2096-78-8 vinyldiphenylphosphine oxide 

Downstream Products

• 138866-01-0 7,7-dimethyl-1-oxo-1-phenyl-3-diphenylphosphinyl-hexahydro-1H-pyrrolo<1,2-c><1,3,2>oxazaphosphorine 
• 138884-67-0 (3R,4aR)-3-(Diphenyl-phosphinoyl)-7,7-dimethyl-1-phenyl-hexahydro-pyrrolo[1,2-c][1,3,2]oxazaphosphinine 
• 138866-00-9 (S)-2-((S)-5,5-Dimethyl-pyrrolidin-2-yl)-1-(diphenyl-phosphinoyl)-ethanol 

Relevant academic research and scientific papers

The Regioselectivity of Nitrone Cycloadditions to Vinyl Phosphorus Compounds

The 1,3-dipolar cycloadditions of nitrones 1-5 to diphenylvinylphosphine oxide (6), sulfide (7) and selenide (8) were carried out.The cycloadditions of the nitrone 3, as a model, to substituted vinylphosphorus derivatives 28-36 were also carried out with

REGIOCHEMICAL STEERING AND ASSIGNMENT IN CYCLOADDITIONS OF NITRONES TO DIPHENYLVINYLPHOSPHINE OXIDE

In 1,3-dipolar cycloaddition of C,N-diphenylnitrone to diphenylvinylphosphine oxide ( and also to diphenylvinylphophine sulphide) the 4-substituted phosphinyl isooxazolidine is formed predominantly and in the case of a cylic nitrone the 5-substituted regioisomer prevails.Regiochemical distinctions between the isomeric phosphinyl isoxazolidines are best executed by means of (13)C NMR spectroscopy. Key words: 1,3-dipolar cycloaddition; diphenylvinylphosphine oxide, C,N-diphenyl nitrone; phosphinyloxazolidine, regioselective addition.