125157-98-4

Basic information

• Product Name: 5,9,11-trimethyl-5H-indolo[2,3-b]quinoline
• Synonyms: 5,9,11-Trimethyl-5H-indolo[2,3-b]quinoline; 5H-quinindoline, 5,9,11-trimethyl-
• CAS NO: 125157-98-4
• Molecular Formula: C₁₈H₁₆N₂
• Molecular Weight: 260.333
• Mol File: 125157-98-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 412.2°C at 760 mmHg
• Flash Point: 203.1°C
• Density: 1.17g/cm³
• Vapor Pressure: 5.29E-07mmHg at 25°C
• Refractive Index: 1.661
• CAS DataBase Reference: 5,9,11-trimethyl-5H-indolo[2,3-b]quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 5,9,11-trimethyl-5H-indolo[2,3-b]quinoline(125157-98-4)
• EPA Substance Registry System: 5,9,11-trimethyl-5H-indolo[2,3-b]quinoline(125157-98-4)

Safety Data

• Hazardous Substances Data: 125157-98-4(Hazardous Substances Data)

Upstream product

• 77-78-1 dimethyl sulfate 
• 132461-45-1 3,5-Dimethyl-11H-10,11-diaza-benzo[b]fluorene 
• 331711-88-7 4-methyl-N-(p-tolyl)quinolin-2-amine 
• 607-66-9 4-methylquinolin-2-ol 
• 634-47-9 2-chloro-4-methylquinoline 
• 132445-58-0 4-Methyl-N¹-(4-methyl-quinolin-2-yl)-benzene-1,2-diamine 
• 132445-59-1 4-methyl-2-(5-methyl-1-benzotriazolo)quinoline 
• 132445-57-9 4-methyl-2-(4-methyl-2-nitroanilino)quinoline 
• 89-62-3 4-methyl-2-nitroaniline 

Relevant articles and documents

Heteroatom directed photoannulation: synthesis of indoloquinoline alkaloids: cryptolepine, cryptotackieine, cryptosanguinolentine, and their methyl derivatives

A three-step synthesis of indoloquinoline alkaloids is described. The reaction of 2,3 and 4-substituted haloquinolines with anilines afforded the respective anilinoquinolines, which upon photocyclization gave the indoloquinolines. By regioselective methylation on quinoline nitrogen, furnished the alkaloids cryptotackieine, cryptosanguinolentine, cryptolepine, and the synthetic isomer isoneocryptolepine. Their methyl derivatives were also synthesized in search of new antiplasmodial drugs and DNA intercalating agents.