1251575-59-3Relevant academic research and scientific papers
A facile and efficient approach to N-protected-β-sulfinylenamines via C-sulfinylation of enamides and enecarbamates
Li, Yinhui,Cheng, Ke,Lu, Xiaoxia,Suna, Jian
supporting information; experimental part, p. 1876 - 1880 (2010/10/20)
A practical method has been developed for the C-sulfinylation of enamides and enecarbamates using sodium phenylsulfinate/methyltrichlorosilane (PhSO 2Na/MeSiCl3) as the sulfinylating reagent and N,N-dimethylacetamide (DMAc) as the Lewis base promoter, which allows for the preparation of a variety of N-protected-β-sulfinylenamines in high yields and good stereoselectivities. The Lewis base is found to be important for both the in situ generation of the active sulfinylating species (PhSOCl) and the sulfinylation step.
