Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1251581-90-4

(3-Amino-5-bromobenzofuran-2-yl)(4-nitrophenyl)methanone is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1251581-90-4 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 1251581-90-4 Structure

  • Basic information

    1. Product Name: (3-Amino-5-bromobenzofuran-2-yl)(4-nitrophenyl)methanone
    2. Synonyms: (3-Amino-5-bromobenzofuran-2-yl)(4-nitrophenyl)methanone
    3. CAS NO:1251581-90-4
    4. Molecular Formula:
    5. Molecular Weight: 361.151
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1251581-90-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (3-Amino-5-bromobenzofuran-2-yl)(4-nitrophenyl)methanone(CAS DataBase Reference)
    10. NIST Chemistry Reference: (3-Amino-5-bromobenzofuran-2-yl)(4-nitrophenyl)methanone(1251581-90-4)
    11. EPA Substance Registry System: (3-Amino-5-bromobenzofuran-2-yl)(4-nitrophenyl)methanone(1251581-90-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1251581-90-4(Hazardous Substances Data)

1251581-90-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1251581-90-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,1,5,8 and 1 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1251581-90:
(9*1)+(8*2)+(7*5)+(6*1)+(5*5)+(4*8)+(3*1)+(2*9)+(1*0)=144
144 % 10 = 4
So 1251581-90-4 is a valid CAS Registry Number.

1251581-90-4Relevant articles and documents

Identification of benzofurano[3,2-d]pyrimidin-2-ones, a new series of HIV-1 nucleotide-competing reverse transcriptase inhibitors

Tremblay, Martin,Bethell, Richard C.,Cordingley, Michael G.,Deroy, Patrick,Duan, Jianmin,Duplessis, Martin,Edwards, Paul J.,Faucher, Anne-Marie,Halmos, Ted,James, Clint A.,Kuhn, Cyrille,Lacoste, Jean-éric,Lamorte, Louie,Laplante, Steven R.,Malenfant, éric,Minville, Joannie,Morency, Louis,Morin, Sébastien,Rajotte, Daniel,Salois, Patrick,Simoneau, Bruno,Tremblay, Sonia,Sturino, Claudio F.

, p. 2775 - 2780 (2013)

Screening of our sample collection led to the identification of a set of benzofurano[3,2-d]pyrimidine-2-one hits acting as nucleotide-competing HIV-1 reverse transcriptase inhibitiors (NcRTI). Significant improvement in antiviral potency was achieved when substituents were introduced at positions N1, C4, C7 and C8 on the benzofuranopyrimidone scaffold. The series was optimized from low micromolar enzymatic activity against HIV-1 RT and no antiviral activity to low nanomolar antiviral potency. Further profiling of inhibitor 30 showed promising overall in vitro properties and also demonstrated that its potency was maintained against viruses resistant to the other major classes of HIV-1 RT inhibitors.

INHIBITORS OF HIV REPLICATION

-

Page/Page column 49, (2010/11/03)

Compounds of formula (I): wherein R1, R2, A1, A2, A3, A4, X and Y are as defined herein, are useful as inhibitors of HIV replication.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1251581-90-4