125159-84-4Relevant academic research and scientific papers
C-amidoalkylation of pyrroles with N-trifluoromethylsulfonyl and N-arylsulfonyl polychloroaldehyde imines
Kondrashov,Rudyakova,Rozentsveig,Rozentsveig,Chernyshev,Krivdin,Levkovskaya
experimental part, p. 1365 - 1374 (2010/01/11)
N-(Trifluoromethylsulfonyl) and N-arylsulfonyl polychloroacetaldehyde imines reacted with pyrrole, 1-alkyl-, 1-benzyl-, and 1-(4-nitrophenyl)- substituted pyrroles, and bis-pyrroles to give the corresponding 2-[1-(sulfonylamino)polychloroethyl]-1H-pyrroles or mixtures of 2- and 3-[1-(sulfonylamino)polychloroethyl]-1H-pyrroles, depending on the nature of the Schiff base and substituent on the pyrrole nitrogen atom and reaction conditions. The first synthesis of 2,5-disubstituted NH-pyrrole by reaction of pyrrole with Schiff bases was described.
N-(2,2,2-TRICHLOROETHYLIDENE)ARENESULFONAMIDES IN THE C-AMIDOALKYLATION OF PYRROLES
Mirskova, A. N.,Drozdova, T. I.,Levkovskaya, G. G.,Kukharev, B. F.,Kalikhman, I. D.,Voronkov, M. G.
, p. 1179 - 1181 (2007/10/02)
The C-amidoalkylation of pyrrole and its derivatives by N-(2,2,2-trichloroethylidene)arenesulfonamides takes place regiospecifically at position 2 of the pyrrole ring with the formation of N-arenesulfonamides.
