Cas 1251908-09-4,4-[(1-benzylpyrrolidin-3-yl)amino]-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[2,3-b]pyridine-5-carbonitrile

1251908-09-4

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Basic information

Product Name: 4-[(1-benzylpyrrolidin-3-yl)amino]-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[2,3-b]pyridine-5-carbonitrile
Synonyms: 4-[(1-benzylpyrrolidin-3-yl)amino]-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[2,3-b]pyridine-5-carbonitrile
CAS NO:1251908-09-4
Molecular Formula:
Molecular Weight: 447.655
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 4-[(1-benzylpyrrolidin-3-yl)amino]-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[2,3-b]pyridine-5-carbonitrile(CAS DataBase Reference)
NIST Chemistry Reference: 4-[(1-benzylpyrrolidin-3-yl)amino]-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[2,3-b]pyridine-5-carbonitrile(1251908-09-4)
EPA Substance Registry System: 4-[(1-benzylpyrrolidin-3-yl)amino]-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[2,3-b]pyridine-5-carbonitrile(1251908-09-4)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1251908-09-4(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1251908-09-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,1,9,0 and 8 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1251908-09:
(9*1)+(8*2)+(7*5)+(6*1)+(5*9)+(4*0)+(3*8)+(2*0)+(1*9)=144
144 % 10 = 4
So 1251908-09-4 is a valid CAS Registry Number.

1251908-09-4Upstream product

1251908-09-4Downstream Products

1251908-15-2 4-[(1-benzylpyrrolidin-3-yl)amino]-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde

1251908-09-4Relevant academic research and scientific papers

CONDENSED PYRROLOPYRIDINE DERIVATIVE

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Page/Page column 22, (2012/02/15)

[Problem] The present invention provides a condensed pyrrolopyridine derivative which is useful as an active ingredient for a pharmaceutical composition, in particular, a pharmaceutical composition for preventing or treating diseases caused by undesirable cytokine signal transduction or diseases caused by abnormal cytokine signal transduction. [Means for Solution] The present inventors have extensively studied a compound having a JAK inhibitory action, and as a result, they have found that a condensed pyrrolopyridine derivative which is the compound of the present invention has an excellent JAK inhibitory action, and is therefore useful as an agent for preventing or treating diseases caused by undesirable cytokine signal transduction or diseases caused by abnormal cytokine signal transduction, thereby completing the present invention.

FUSED PYRROLOPYRIDINE DERIVATIVE

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Page/Page column 32, (2012/03/11)

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