1251928-27-4

Basic information

• Product Name: 4-[2-(4-methoxyphenyl)imidazo[4,5-b]indol-3(4H)-yl]phenol
• CAS NO: 1251928-27-4
• Molecular Weight: 355.396
• Mol File: 1251928-27-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[2-(4-methoxyphenyl)imidazo[4,5-b]indol-3(4H)-yl]phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[2-(4-methoxyphenyl)imidazo[4,5-b]indol-3(4H)-yl]phenol(1251928-27-4)
• EPA Substance Registry System: 4-[2-(4-methoxyphenyl)imidazo[4,5-b]indol-3(4H)-yl]phenol(1251928-27-4)

Safety Data

• Hazardous Substances Data: 1251928-27-4(Hazardous Substances Data)

Upstream product

• 67097-24-9 4-[(4-methoxybenzylidene)amino]phenol 
• 91-56-5 indole-2,3-dione 

Relevant articles and documents

Microwave-assisted, solvent-free and parallel synthesis of some novel substituted imidazoles of biological interest

Solvent free microwave assisted synthesis of some novel substituted imidazoles of biological interest is reported. First, primary aromatic or heteryl amine was condensed with aryl or heteryl aldehydes to afford corresponding Schiff's base. The Schiff's base further on treatment with ammonium acetate (NH4OAC) and isatin using silica gel as the solid support, yielded the corresponding aryl imidazoles. In this paper a comparative study between the developed microwave method and conventional method is described. The synthesized compounds were analyzed by physical and analytical data. The synthesized compounds were evaluated for their antibacterial, anthelmintic, short-term anticancer and antitubercular activity. All the synthesized substituted imidazoles have shown good antibacterial activity against gram negative bacterial strains Klebsiella pneumoniae and Escherichia coli and moderate to good anthelmintic activity. The synthesized imidazole derivative possessed signifi-cant cytotoxic activity against Ehrlich's ascites carcinoma (EAC) cell lines. None of the compounds exhibited prominent antitubercular activity.