1251957-60-4

Basic information

• Product Name: C₁₅H₂₄⁽¹²⁵⁾INO₃
• CAS NO: 1251957-60-4
• Molecular Weight: 391.36
• Mol File: 1251957-60-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₅H₂₄⁽¹²⁵⁾INO₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₂₄⁽¹²⁵⁾INO₃(1251957-60-4)
• EPA Substance Registry System: C₁₅H₂₄⁽¹²⁵⁾INO₃(1251957-60-4)

Safety Data

• Hazardous Substances Data: 1251957-60-4(Hazardous Substances Data)

Upstream product

• 56392-17-7 metoprolol tartrate 

Relevant articles and documents

Preparation of radioiodo-metoprolol and its biological evaluation as a possible cardiac imaging agent1

125I-Metoprolol was prepared by electrophilic substitution reaction in the presence of Chloramine-T (CAT) as an oxidizing agent. The reaction conditions were optimized. The radiochemical yield of 125I-metoprolol exceeding 90% was attained in 10 min at ambient temperature (25 ± 1°C). The radiochemical yield and purity of the labeled product were evaluated by electrophoresis, thin-layer chromatography (TLC), and high-performance liquid chromatography (HPLC). Biodistribution studies of 125I-iodometoprolol were carried out in normal Albino Swiss mice. The results indicate the possibility of using [125I]- iodometoprolol for myocardial imaging. Pleiades Publishing, Inc., 2010.