1252015-01-2

Basic information

• Product Name: (E)-1-(benzo[d][1,3]dioxol-5-yl)-3-(2-nitrophenyl)prop-2-en-1-one
• Synonyms: (E)-1-(benzo[d][1,3]dioxol-5-yl)-3-(2-nitrophenyl)prop-2-en-1-one
• CAS NO: 1252015-01-2
• Molecular Weight: 297.267
• Mol File: 1252015-01-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (E)-1-(benzo[d][1,3]dioxol-5-yl)-3-(2-nitrophenyl)prop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(benzo[d][1,3]dioxol-5-yl)-3-(2-nitrophenyl)prop-2-en-1-one(1252015-01-2)
• EPA Substance Registry System: (E)-1-(benzo[d][1,3]dioxol-5-yl)-3-(2-nitrophenyl)prop-2-en-1-one(1252015-01-2)

Safety Data

• Hazardous Substances Data: 1252015-01-2(Hazardous Substances Data)

Upstream product

• 274-09-9 Methylenedioxybenzene 
• 3162-29-6 1-(benzo[d][1,3]dioxol-6-yl)ethanone 
• 552-89-6 2-nitro-benzaldehyde 

Downstream Products

• 1575481-10-5 3-(benzo[d][1,3]dioxol-5-yl)-5-(2-nitrophenyl)-1-phenyl-1H-pyrazole 
• 6808-65-7 Dubamine 

Relevant articles and documents

Synthesis and characterization of novel benzo[d][1,3]dioxole gathered pyrazole derivatives and their antimicrobial evaluation

Benzo[d][1,3]dioxole gathered pyrazole derivatives (4a-i) were synthesized by the reaction of chalcones with phenyl hydrazine in presence of absolute alcohol as a solvent. Chalcones were prepared by the Claisen-Schmidt reaction between 1-(benzo[d][1,3]dioxol-5-yl)ethanone (2) and substituted aromatic aldehydes. The synthesized compounds were characterized by spectral and elemental analysis data. Furthermore, Benzo[ d][1,3]dioxole gathered pyrazole derivatives (4a-i) were evaluated for their in vitro antimicrobial activity. Among the newly synthesized compounds 4a, 4c, 4 g and 4 h showed the excellent antifungal activity and as well as 4a and 4d showed the excellent antibacterial activity when compared to other compounds. Springer Science+Business Media 2014.