1252026-08-6Relevant articles and documents
Evidence for the bioactivation of 4-nonylphenol to quinone methide and ortho -benzoquinone metabolites in human liver microsomes
Deng, Pan,Zhong, Dafang,Nan, Fajun,Liu, Sheng,Li, Dan,Yuan, Tao,Chen, Xiaoyan,Zheng, Jiang
, p. 1617 - 1628 (2011/03/19)
4-Nonylphenol (4-NP) is a well-known toxic environmental contaminant. The major objective of the present study was to identify reactive metabolites of 4-NP. Following incubations of 4-NP with NADPH- and GSH-supplemented human liver microsomes, 6 GSH conju