125209-79-2

Usage

Uses

Used in Organic Synthesis:
3-(2-(2-aminopyridin-3-yl)disulfanyl)pyridin-2-amine is used as a synthetic intermediate for the preparation of various organic compounds due to the reactivity of its disulfanyl group, which can participate in a range of useful chemical reactions.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 3-(2-(2-aminopyridin-3-yl)disulfanyl)pyridin-2-amine is used as a lead compound for the development of new drugs, leveraging its amine and pyridine groups which are commonly found in biologically active molecules, potentially leading to the discovery of novel therapeutic agents.
Used in Chemical Research:
3-(2-(2-aminopyridin-3-yl)disulfanyl)pyridin-2-amine serves as a subject of study in chemical research, where its unique structure and properties are investigated to understand its reactivity, stability, and potential applications in various chemical processes.

Upstream product

• 173278-49-4 2-tert-butylthiazolo<4,5-b>pyridine 
• 110402-20-5 2-aminopyridine-3-thiol 

Downstream Products

• 110402-20-5 2-aminopyridine-3-thiol 
• 173278-51-8 3-mercapto-2(1H)-pyridinone 

Relevant academic research and scientific papers

First synthesis of 3-mercapto-2(1H)-pyridinone, a simple disubstituted pyridine useful for synthesis of the 4-azaphenoxathiine ring system and its novel diazaphenoxathiine analogs: 1,6-Diazaphenoxathiine and 2,6-diazaphenoxathiine

3-Mercapto-2(1H)-pyridinone (1) can be synthesized in three simple high-yielding steps from readily available 2-tert-butylthiazolo[4,5-b]pyridine (2). Its disodium salt condenses with o-chloronitrobenzene, 2-chloro-3-nitropyridine, and 3-chloro-4-nitropyridine 1-oxide to give respectively 4-azaphenoxathiine (10), 1,6-diazaphenoxathiine (12), and 2,6-diazaphenoxathiine 2-oxide (14) which reduces to 2,6-diazaphenoxathiine (15). The structures of these previously unreported azaphenoxathiine systems were confirmed by assignment of their respective 13C NMR spectra.

CARBACEPHEM β-LACTAM ANTIBIOTICS

Carbacephem -lactam antibiotics having structure (I) are disclosed, including stereoisomers, pharmaceutically acceptable salts, esters and prodrugs thereof, wherein Ar1, Ar2, R1 and R2 are as defined herein. The compounds are useful for the treatment of bacterial infections, in particular those caused by methicillin-resistant Staphylococcus spp.

CARBACEPHEM β-LACTAM ANTIBIOTICS

Carbacephem β-lactam antibiotics having the following chemical structures (I) and (II) are disclosed, including stereoisomers, pharmaceutically acceptable salts, esters and prodrugs thereof, wherein Ar2, R1, R2 and R3 are as defined herein. The compounds are useful for the treatment of bacterial infections, in particular those caused by methicillin-resistant Staphylococcus spp.