125219-62-7

Basic information

• Product Name: 2,6-diamino-4-(pyridin-4-yl)-4H-thiopyran-3,5-dicarbonitrile
• Synonyms: 2,6-diamino-4-(pyridin-4-yl)-4H-thiopyran-3,5-dicarbonitrile
• CAS NO: 125219-62-7
• Molecular Weight: 255.303
• Mol File: 125219-62-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,6-diamino-4-(pyridin-4-yl)-4H-thiopyran-3,5-dicarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-diamino-4-(pyridin-4-yl)-4H-thiopyran-3,5-dicarbonitrile(125219-62-7)
• EPA Substance Registry System: 2,6-diamino-4-(pyridin-4-yl)-4H-thiopyran-3,5-dicarbonitrile(125219-62-7)

Safety Data

• Hazardous Substances Data: 125219-62-7(Hazardous Substances Data)

Upstream product

• 872-85-5 pyridine-4-carbaldehyde 
• 7357-70-2 Cyanothioacetamide 
• 109-77-3 malononitrile 
• 63080-75-1 4-pyridinylmethylenepropanedinitrile 

Relevant articles and documents

CYCLIZATION OF NITRILES. XXXIII. SYNTHESIS AND STRUCTURE OF 4-ARYL-2,6-DIAMINO-3,5-DICYANOTHIOPYRANS AND THEIR RECYCLIZATION TO 6-AMINO-4-ARYL-3,5-DICYANO-2(1H)-PYRIDINETHIONES

Like the three-component condensation of aromatic aldehydes, malononitrile, and cyanothioacetamide, the reaction of arylidenemalononitriles with cyanothioacetamide and of arylidenecyanothioacetamides with malononitrile leads to the formation of 4-aryl-2,6-diamino-3,5-dicyano-4H-thiopyrans.It was established by x-ray crystallographic investigation that the 4H-thiopyran ring in the obtained compounds has the boat conformation.Under the influence of bases the 4H-thiopyrans readily undergo recyclization to 6-amino-4-aryl-3,5-dicyano-2(1H)-pyridinethiones.