125237-82-3

Upstream product

• 123573-84-2 2-(diphenylphosphonooxy)ethyl 2-deoxy-4,6-O-isopropylidene-2-(2,2,2-trichloroethoxycarbonylamino)-α-D-glucopyranoside 
• 112-64-1 tetradecanoyl chloride 
• 123573-83-1 2-hydroxyethyl 2-deoxy-4,6-O-isopropylidene-2-(2,2,2-trichloroethoxycarbonylamino)-α-D-glucopyranoside 
• 123573-82-0 2-hydroxyethyl 2-deoxy-2-(2,2,2-trichloroethoxycarbonylamino)-α-D-glucopyranoside 

Downstream Products

• 123573-86-4 2-(diphenylphosphonooxy)ethyl 2-deoxy-2-(N-dodecanoylglycylamino)-4,6-O-isopropylidene-3-O-tetradecanoyl-α-D-glucopyranoside 
• 123598-20-9 2-(diphenylphosphonooxy)ethyl 2-deoxy-2-(N-dodecanoylglycylamino)-3-O-tetradecanoyl-α-D-glucopyranoside 
• 777022-37-4 Tetradecanoic acid (4aR,6S,7R,8R,8aS)-7-amino-6-[2-(diphenoxy-phosphoryloxy)-ethoxy]-2,2-dimethyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl ester 

Relevant academic research and scientific papers

Synthesis and biological activities of lipid A analogs: Modification of a glycosidically bound group with chemically stable polar acidic groups and lipophilic groups on the disaccharide backbone with tetradecanoyl or N-dodecanoylglycyl groups

Six novel lipid A analogs were synthesized. The first two analogs, 4 and 5, have an α-glycosidically bound carboxymethyl or 1,3-dicarboxyisopropyl group on the disaccharide backbone with four tetradecanoyl groups. The next three analogs, 6, 7 and 8, have