1252577-35-7Relevant articles and documents
Synthesis of 3-substituted 1-thioacyl- and 1-thiocarbamoylindoles from-substituted 2-isocyanato-β-methoxystyrenes
Fukamachi, Shuhei,Fujita, Seiki,Murahashi, Kazuya,Konishi, Hisatoshi,Kobayashi, Kazuhiro
experimental part, p. 2985 - 2989 (2010/11/04)
3-Aryl-1-thioacylindoles were prepared by treating α-aryl-2- isothiocyanato-β-methoxystyrenes with organolithiums or Grignard reagents, followed by hydriodic acid catalyzed cyclization of the resulting adducts. A one-pot synthesis of 1-thiocarbamoylindoles was achieved by hydriodic acid mediated cyclization of the corresponding thiourea intermediates, prepared from α-substituted 2-isothiocyanato-β-methoxystyrenes and secondary amines. Georg Thieme Verlag Stuttgart New York.