1252617-33-6

Basic information

• Product Name: (E)-3-(4-(tert-butyl)phenyl)-1-(p-tolyl)prop-2-en-1-one
• Synonyms: (E)-3-(4-(tert-butyl)phenyl)-1-(p-tolyl)prop-2-en-1-one
• CAS NO: 1252617-33-6
• Molecular Weight: 278.394
• Mol File: 1252617-33-6.mol

Chemical Properties

• CAS DataBase Reference: (E)-3-(4-(tert-butyl)phenyl)-1-(p-tolyl)prop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-(4-(tert-butyl)phenyl)-1-(p-tolyl)prop-2-en-1-one(1252617-33-6)
• EPA Substance Registry System: (E)-3-(4-(tert-butyl)phenyl)-1-(p-tolyl)prop-2-en-1-one(1252617-33-6)

Safety Data

• Hazardous Substances Data: 1252617-33-6(Hazardous Substances Data)

Usage

Uses

Used in Fragrance Industry:
(E)-3-(4-(tert-butyl)phenyl)-1-(p-tolyl)prop-2-en-1-one is used as a fragrance ingredient for its floral, orange-blossom scent, adding a pleasant aroma to consumer products such as perfumes, soaps, and lotions. Its ability to provide a fresh and natural scent makes it a valuable addition to the fragrance industry.
Used in Organic Synthesis:
In the field of organic chemistry, (E)-3-(4-(tert-butyl)phenyl)-1-(p-tolyl)prop-2-en-1-one is utilized as a key compound in the synthesis of other organic compounds. Its unique structure allows for various chemical reactions, making it a versatile building block for creating a wide range of molecules with different applications.
Used in Chemical Reactions and Processes:
(E)-3-(4-(tert-butyl)phenyl)-1-(p-tolyl)prop-2-en-1-one also plays a significant role in organic chemical reactions and processes. Its alpha,beta-unsaturated carbonyl structure enables it to participate in various types of reactions, such as electrophilic addition, conjugate addition, and cycloaddition, which are essential for the development of new chemical compounds and materials.

Upstream product

• 1746-23-2 4-tert-Butylstyrene 
• 7163-50-0 (4-methylphenyl)(oxo)acetic acid 
• 122-00-9 para-methylacetophenone 
• 1056474-04-4 (E)-1-(tert-butyl)-4-(2-nitrovinyl)benzene 
• 104-87-0 4-methyl-benzaldehyde 
• 939-97-9 4-tert-Butylbenzaldehyde 
• 201230-82-2 carbon monoxide 
• 624-31-7 4-tolyl iodide 

Downstream Products

• 177752-56-6 3-(4-(tert-butyl)phenyl)-1-(p-tolyl)propan-1-one 

Relevant articles and documents

Visible Light Activated Radical Denitrative Benzoylation of β-Nitrostyrenes: A Photocatalytic Approach to Chalcones

A metal-free, convenient photocatalytic approach to chalcones from β-nitrostyrenes and benzaldehydes via a radical denitrative benzoylation pathway is reported. The salient features of the protocol include the utilization of visible light as an inexpensive and ecosustainable energy source, N-hydroxyphthalimide (NHPI) as a reusable organophotocatalyst and acetonitrile as an acceptable green solvent to afford chalcones in excellent yields at room temperature in a one-pot procedure. Notably, this is the first application of β-nitrostyrenes as readily available substrates for chalcone synthesis and the first example of photocatalysis in this field. (Figure presented.).

Silver-catalyzed decarboxylative cross-coupling of α-keto acids with alkenes giving approach to chalcones

A silver-catalyzed decarboxylative cross-coupling of α-keto acids with alkenes is reported. The method, with a wide range of substrate tolerance and mild operational conditions, can produce various chalcone derivatives in moderate to high yields from easily available starting materials.

Transition-Metal-Free Synthesis of Homo- and Hetero-1,2,4-Triaryl Benzenes by an Unexpected Base-Promoted Dearylative Pathway

An unprecedented approach for the synthesis of homo- and hetero-1,2,4-triaryl benzenes has been developed using a simple base-mediated reaction of either α-aryl cinnamyl alcohols or α,γ-di-aryl propanones. The salient feature of this strategy involves the sequential hydride transfer, regiospecific condensation, regiospecific dearylation, and aromatization under metal-free reaction conditions. The synthesis of unsymmetrically substituted triphenylenes by oxidative coupling of the synthesized 1,2,4-triaryl benzenes has also been demonstrated.

Copper-catalyzed oxidative coupling of alkenes with aldehydes: Direct access to α,β-unsaturated ketones

Let's get radical: The first copper-catalyzed oxidative coupling of alkenes and aldehydes was developed. Various aldehydes were utilized as substrates to construct α,β-unsaturated ketones. A preliminary mechanistic study indicated that this reaction is likely to proceed through a single-electron transfer. Copyright

Development of a general palladium-catalyzed carbonylative heck reaction of aryl halides

The first general palladium-catalyzed carbonylative vinylation of aryl halides with olefins in the presence of CO has been developed. Applying a catalyst system consisting of [(cinnamyl)PdCl]2 and bulky imidazolyl-phosphine ligand L1 allows for the efficient and selective synthesis of α,β-unsaturated ketones under mild reaction conditions. Starting from easily available aryl halides and olefins, versatile building blocks can be prepared in a straightforward manner. The generality and functional group tolerance of this novel protocol is demonstrated.