1252672-36-8Relevant articles and documents
Aminonorbornane derivative and preparation method and application thereof
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Paragraph 0061-0063; 0067-0068, (2020/04/17)
The invention discloses an aminonorbornane derivative and a preparation method and application thereof and relates to a compound having a structure represented by a formula I which is described in thespecification or a pharmaceutically acceptable salt, a solvate, an active metabolite, a polymorph, an ester, an optical isomer or a prodrug thereof, a pharmaceutical composition comprising the compound as shown in the formula I, and application of the compound and the pharmaceutical composition as highly selective Bruton's tyrosine kinase (BTK) inhibitors of BTK (C481S) mutants for preparation ofdrugs used for prevention or treatment of heteroimmune diseases, autoimmune diseases or cancer.
NOVEL AMIDE AND AMIDINE DERIVATIVES AND USES THEREOF
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Page/Page column 32, (2010/11/03)
The present invention relates to inhibitors of 11-β-hydroxysteroid dehydrogenase type 1 enzyme and their use in treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, central nervous system disorders, and diseases and conditions that are related to excessive glucocorticoids.