1252809-29-2Relevant academic research and scientific papers
Divergent, stereoselective access to heterocyclic α,α-quaternary- and β2,3,3-amino acid derivatives from a N-Pmp-protected Orn-derived β-lactam
Nú?ez-Villanueva, Diego,García-López, M. Teresa,Martín-Martínez, Mercedes,González-Mu?iz, Rosario
, p. 5195 - 5201 (2015)
A suitably protected Orn-derived (3S,4S)-β-lactam was used as common intermediate in the synthesis of conformationally constrained (3S,4S)-2-oxoazepane α,α- and (2S,3S)-2-oxopiperidine-β2,3,3-amino acid derivatives. Compared to alternative proc
Quaternary α,α-2-oxoazepane α-amino acids: Synthesis from ornithine-derived β-lactams and incorporation into model dipeptides
Nunez-Villanueva, Diego,Bonache, M. Angeles,Infantes, Lourdes,Garcia-Lopez, M. Teresa,Martin-Martinez, Mercedes,Gonzalez-Muniz, Rosario
, p. 6592 - 6603 (2011/10/04)
To explore further the chemistry of amino acid-derived β-lactams, their conversion to α,α-heterocyclic quaternary amino acid derivatives is investigated. The latter derivatives, containing 2-oxoazepane as the α,α-substituent, are synthesized by a simple P
