125281-43-8

Basic information

• Product Name: (S)-4,5-Bis-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyloxycarbonylamino)-pentanoic acid
• CAS NO: 125281-43-8
• Molecular Weight: 496.688
• Mol File: 125281-43-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-4,5-Bis-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyloxycarbonylamino)-pentanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4,5-Bis-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyloxycarbonylamino)-pentanoic acid(125281-43-8)
• EPA Substance Registry System: (S)-4,5-Bis-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyloxycarbonylamino)-pentanoic acid(125281-43-8)

Safety Data

• Hazardous Substances Data: 125281-43-8(Hazardous Substances Data)

Upstream product

• 14602-86-9 (1R,2S,5R)-menthyl chloroformate 
• 89717-54-4 (R,S)-4,5-diaminopentanoic acid dihydrochloride 

Downstream Products

• 125281-42-7 (S)-4,5-Bis-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyloxycarbonylamino)-pentanoic acid ethyl ester 

Relevant articles and documents

Approach to Chiral Vicinal Diacylamines by Bamberger Ring Cleavage of Substituted Imidazoles

Ring cleavage of ethyl 3-propanoate (1) with (-)-menthyl chloroformate introduces chiral carbamate substituents on the double bond which, upon hydrogenation, induces preferred formation of ethyl (4S)-4,5-bispentanoate (5) (5:1 ratio of diastereomers).The ring cleavage benzoylation product of (S)-histidine methyl ester, with a chiral center in the side chain, gives rise to (2S,4R)/(2S,4S)-2,4,5-tribenzamidopentanoates (13, 14), in 2:1 ratio upon hydrogenation.