1253043-75-2Relevant academic research and scientific papers
Memory of chirality in cascade rearrangements of enediynes
Nechab, Malek,Campolo, Damien,Maury, Julien,Perfetti, Patricia,Vanthuyne, Nicolas,Siri, Didier,Bertrand, Michele P.
supporting information; experimental part, p. 14742 - 14744 (2011/02/16)
The cascade rearrangement of chiral enediynes 1c-e, involving successively 1,3-proton shift, Saito-Myers cyclization, 1,5-hydrogen atom transfer, and intramolecular coupling of the resulting biradical, proceeded at 80°C to form tri- and tetracyclic heterocycles possessing a quaternary stereogenic center with a very high level of memory of chirality.
