125308-41-0

Upstream product

• 152961-83-6 (S)-2-Benzyl-3-<(p-tolylsulfonyl)oxy>propyl acetate 
• 1634-04-4 tert-butyl methyl ether 
• 98-59-9 p-toluenesulfonyl chloride 
• 110270-49-0 (R)-3-acetoxy-2-benzyl-1-propanol 

Downstream Products

• 123938-00-1 (S)-2-Benzyl-3-(propane-2-sulfonyl)-propionic acid methyl ester 
• 116622-69-6 (S)-2-benzyl-3-isopropylsulfonyl-propionic acid 
• 125308-43-2 ((S)-3-Isopropylsulfanyl-2-methoxymethoxymethyl-propyl)-benzene 
• 125308-44-3 (S)-2-Isopropylsulfanylmethyl-3-phenyl-propan-1-ol 
• 125308-42-1 Toluene-4-sulfonic acid (S)-2-methoxymethoxymethyl-3-phenyl-propyl ester 

Relevant academic research and scientific papers

Sulfonic acid ester derivatives, method for production thereof and use thereof

Novel and useful optical active 2-aralkyl-3-sulfonyloxy-1-propanol and 2-aralkyl-3-sulfonyloxypropionic acid are provided by using an optical active 2-aralkyl-3-acyloxy-1-propanol as a starting material. Furthermore, an optical active 2-aralkyl-3-thiopropionic acid, which is an important intermediate of enkephalinase inhibitor, is provided. According to the present invention, industrially useful optical active sulfonic acid ester derivatives can be provided.

LIPASE-CATALYZED ASYMMETRIC SYNTHESIS OF CHIRAL 1,3-PROPANEDIOLS AND ITS APPLICATION TO THE PREPARATION OF OPTICALLY PURE BUILDING BLOCK FOR RENIN INHIBITORS

Asymmetric synthesis of chiral 2-substituted-1,3-propanediols was realized the lipase-catalyzed transesterification in vinyl acetate and it was applied to the synthesis of an optically active sulfone derivate.