1253202-35-5 Usage
Uses
Used in Pharmaceutical Industry:
(R)-3-Chloro-2-((4-(trifluoroMethoxy)benzyl)oxy)propyl 4-Methoxybenzoate is used as an intermediate in the synthesis of novel anti-tuberculosis drugs. Its unique structure allows for the development of new compounds with enhanced efficacy and reduced side effects in the treatment of tuberculosis.
Specifically, it is used in the synthesis of (S)-PA 824 (P122500), a promising anti-tuberculosis drug candidate. The compound's role in the synthesis process is crucial, as it contributes to the formation of the final drug product with desired pharmacological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 1253202-35-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,3,2,0 and 2 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1253202-35:
(9*1)+(8*2)+(7*5)+(6*3)+(5*2)+(4*0)+(3*2)+(2*3)+(1*5)=105
105 % 10 = 5
So 1253202-35-5 is a valid CAS Registry Number.
1253202-35-5Relevant academic research and scientific papers
A concise and convergent synthesis of PA-824
Marsini, Maurice A.,Reider, Paul J.,Sorensen, Erik J.
supporting information; experimental part, p. 7479 - 7482 (2010/12/25)
An efficient four-step synthesis of PA-824, a promising antituberculosis drug candidate, has been developed. This concise approach offers significant improvements over the synthetic route currently used for large-scale production.
