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1253203-57-4

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1253203-57-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1253203-57-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,3,2,0 and 3 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1253203-57:
(9*1)+(8*2)+(7*5)+(6*3)+(5*2)+(4*0)+(3*3)+(2*5)+(1*7)=114
114 % 10 = 4
So 1253203-57-4 is a valid CAS Registry Number.

1253203-57-4Downstream Products

1253203-57-4Relevant articles and documents

Design, Synthesis and Preliminary Evaluation of Novel Imperatorin Derivatives as Vasorelaxant Agents

Li, Na,He, Jianyu,Zhan, Yingzhuan,Zhou, Nan,Zhang, Jie

, p. 18 - 23 (2011)

A series of novel imperatorin derivatives were synthesized from commercially available xanthotoxin. The in vitro pharmacological evaluation indicated that all of the compounds possessed potent vasodilatory activity. Among them, compounds (5b), (5d) and (5e) exhibited higher vasdilatory activity (with EC50 values of 0.68 μM, 0.59 μM and 0.49 μM, respectively) than imperatorin (EC50 = 1.12 μM). The program Volsurf was used to predict the derivatives' ADMErelevant descriptors. The results suggested that these novel compounds had a potential interest for the development of novel and potent vasorelaxant agents.

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