1253286-02-0Relevant academic research and scientific papers
Asymmetric carbonyl-ene reaction of trifluoropyruvate catalyzed by Pd(II)-SunPhos complex
Jiang, Lili,Hu, Bei,Xie, Xiaomin,Zhang, Zhaoguo
, p. 6901 - 6905 (2017)
An efficient asymmetric carbonyl-ene reaction of trifluoropyruvate catalyzed by chiral Pd(II)/(S)-SunPhos complex was developed. A series of optically active homoallylic alcohols containing a CF3 group were obtained with high yields and excellent ee under mild conditions. Particularly, the reaction of isobutylene and trifluoropyruvate gave the desired product (90% yield, 98% ee) with catalyst loading as low as 0.01 mol% in dichloroethane/toluene.
Asymmetric carbonyl-ene and Friedel-Crafts reactions catalysed by Lewis acid platinum group metal complexes of the enantiopure atropisomeric biaryl-like diphosphine (S)-Me2-CATPHOS: A comparison with BINAP
Doherty, Simon,Knight, Julian G.,Mehdi-Zodeh, Hamid
experimental part, p. 209 - 216 (2012/06/04)
Lewis acid platinum and palladium complexes of (S)-Me2-CATPHOS catalyse the carbonyl-ene reaction between allylbenzene derivatives and ethyl trifluoropyruvate to give the expected α-hydroxy esters with ee's up to 97%, while the corresponding re
