1253291-28-9

Basic information

• Product Name: Methanone, [4-(difluoroMethoxy)-3-[2-(2-pyridinyl)ethynyl]phenyl](5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-, hydrochloride (1:1)
• Synonyms: Methanone, [4-(difluoroMethoxy)-3-[2-(2-pyridinyl)ethynyl]phenyl](5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-, hydrochloride (1:1)
• CAS NO: 1253291-28-9
• Molecular Formula: C₂₂H₁₅F₂N₃O₂*ClH
• Molecular Weight: 427.84
• EINECS: -0
• Mol File: 1253291-28-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Methanone, [4-(difluoroMethoxy)-3-[2-(2-pyridinyl)ethynyl]phenyl](5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-, hydrochloride (1:1)(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, [4-(difluoroMethoxy)-3-[2-(2-pyridinyl)ethynyl]phenyl](5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-, hydrochloride (1:1)(1253291-28-9)
• EPA Substance Registry System: Methanone, [4-(difluoroMethoxy)-3-[2-(2-pyridinyl)ethynyl]phenyl](5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-, hydrochloride (1:1)(1253291-28-9)

Safety Data

• Hazardous Substances Data: 1253291-28-9(Hazardous Substances Data)

Upstream product

• 15126-06-4 methyl 3-iodo-4-hydroxybenzoate 
• 1197357-97-3 methyl 4-(difluoromethoxy)-3-(pyridin-2-ylethynyl)benzoate 
• 1131614-23-7 4-difluoromethoxy-3-iodo-benzoic acid methyl ester 
• 147740-02-1 6,7-dihydro-5H-pyrrolo[3,4-b]pyridine dihydrochloride 
• 1197357-98-4 4-(difluoromethoxy)-3-(pyridin-2-ylethynyl)benzoic acid 

Relevant articles and documents

BISARYL ALKYNYLAMIDES AS NEGATIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR 5 (MGLUR5)

Disclosed are compounds of Formula (I): pharmaceutical compositions containing compounds of Formula I, and the use of compounds of Formula (I) to treat diseases and disorders including schizophrenia, paranoia, depression, manic-depressive illness and anxiety wherein W1-W5, X1-X4, Y, Z1-Z5, m, n, p, and R1-R6 in Formula (I) are defined in the specification.