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1-[(2-chloro-4-fluorophenyl)methyl]-4-[2-(methyloxy)-5-(4-morpholinyl)phenyl]-2,3-piperazinedione is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1253380-03-8 Structure
  • Basic information

    1. Product Name: 1-[(2-chloro-4-fluorophenyl)methyl]-4-[2-(methyloxy)-5-(4-morpholinyl)phenyl]-2,3-piperazinedione
    2. Synonyms: 1-[(2-chloro-4-fluorophenyl)methyl]-4-[2-(methyloxy)-5-(4-morpholinyl)phenyl]-2,3-piperazinedione
    3. CAS NO:1253380-03-8
    4. Molecular Formula:
    5. Molecular Weight: 447.894
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1253380-03-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-[(2-chloro-4-fluorophenyl)methyl]-4-[2-(methyloxy)-5-(4-morpholinyl)phenyl]-2,3-piperazinedione(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-[(2-chloro-4-fluorophenyl)methyl]-4-[2-(methyloxy)-5-(4-morpholinyl)phenyl]-2,3-piperazinedione(1253380-03-8)
    11. EPA Substance Registry System: 1-[(2-chloro-4-fluorophenyl)methyl]-4-[2-(methyloxy)-5-(4-morpholinyl)phenyl]-2,3-piperazinedione(1253380-03-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1253380-03-8(Hazardous Substances Data)

1253380-03-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1253380-03-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,3,3,8 and 0 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1253380-03:
(9*1)+(8*2)+(7*5)+(6*3)+(5*3)+(4*8)+(3*0)+(2*0)+(1*3)=128
128 % 10 = 8
So 1253380-03-8 is a valid CAS Registry Number.

1253380-03-8Downstream Products

1253380-03-8Relevant articles and documents

DIKETOPIPERAZINE DERIVATIVES AS P2X7 MODULATORS

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Page/Page column 84, (2010/11/17)

The invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof: (I) wherein: A represents an aryl, heteroaryl or heterocyclyl group; and any ring or ring system of said aryl or heteroaryl is optionally substituted with 1 to 3 substituents, which may be the same or different, selected from the group consisting of halogen, C1-6 alkyl, -CF3, - OCF3, cyano, C1-6 alkoxy, -NR10R11, -X-aryl, -X-heteroaryl and -X-heterocyclyl; R1, R2, R3, R4 and R5 independently represent hydrogen, fluorine, chlorine, -CF3, cyano or C1-6 alkyl, such that at least one of R1, R2, R3, R4 and R5 is other than hydrogen; R6, R7, R8, R9, R10 and R11 independently represent hydrogen or C1-6 alkyl; X represents a linker selected from a bond, -(CH2)n- and -O-(CH2)n-; and n represents an integer from 1 to 3. The compounds or salts modulate P2X7 receptor function and are capable of antagonizing the effects of ATP at the P2X7 receptor ("P2X7 receptor antagonists").

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