1253393-88-2Relevant academic research and scientific papers
Effects of structure on inhibitory activity in a series of mechanism-based inhibitors of human neutrophil elastase
Dou, Dengfeng,He, Guijia,Kuang, Rongze,Fu, Qingfong,Venkataraman, Radhika,Groutas, William C.
experimental part, p. 6646 - 6650 (2010/10/18)
A structurally-diverse series of carboxylate derivatives based on the 1,2,5-thiadiazolidin-one 1,1 dioxide scaffold were synthesized and used to probe the S′ subsites of human neutrophil elastase (HNE) and neutrophil proteinase 3 (Pr 3). Several compounds
