1253394-26-1

Basic information

• Product Name: 4-trifluoromethyl-1-methyl-3-(methylthio)-2-phenyl-1H-pyrrole
• Synonyms: 4-trifluoromethyl-1-methyl-3-(methylthio)-2-phenyl-1H-pyrrole
• CAS NO: 1253394-26-1
• Molecular Weight: 271.306
• Mol File: 1253394-26-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-trifluoromethyl-1-methyl-3-(methylthio)-2-phenyl-1H-pyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-trifluoromethyl-1-methyl-3-(methylthio)-2-phenyl-1H-pyrrole(1253394-26-1)
• EPA Substance Registry System: 4-trifluoromethyl-1-methyl-3-(methylthio)-2-phenyl-1H-pyrrole(1253394-26-1)

Safety Data

• Hazardous Substances Data: 1253394-26-1(Hazardous Substances Data)

Upstream product

• 14119-99-4 4-trifluoroacetyl-3-methyl-2-phenyl-1,3-oxazol-3-ium-5-olate 
• 1779-54-0 methylthiomethyl(triphenyl)phosphonium chloride 
• 2181-42-2 trimethylsulphonium iodide 

Relevant articles and documents

The use of sulfur ylides in the synthesis of 3-alkyl(aryl)thio-4- trifluoromethylpyrroles from mesoionic 4-trifluoroacetyl-1,3-oxazolium-5-olates

In this report, we describe a new method for the synthesis of densely functionalized pyrroles. Reaction of mesoionic 1,3-oxazolium-5-olates with various S-ylides proceeds via nucleophilic addition followed by opening of the oxazole ring and subsequent cyclization to multisubstituted pyrroles bearing both a trifluoromethyl and alkyl(aryl)thio group at 3- and 4-positions.