1253579-27-9Relevant academic research and scientific papers
Copper-catalyzed asymmetric addition of arylboronates to isatins: A catalytic cycle involving alkoxocopper intermediates
Shintani, Ryo,Takatsu, Keishi,Hayashi, Tamio
supporting information; experimental part, p. 6822 - 6824 (2010/10/19)
A copper-catalyzed addition of arylboronates to isatins has been developed to give 3-aryl-3-hydroxy-2-oxindoles under mild conditions. The catalytic cycle of this process has been examined through a series of stoichiometric reactions and an effective asymmetric variant has also been described by the use of a chiral N-heterocyclic carbene ligand.
