1253769-38-8

Basic information

• Product Name: (Z)-ethyl-[4-(([6-(N-ethyl-N-methyl-carbamoyl)-2-oxo-1,2-dihydro-indol-3-ylidene]phenylmethyl)amino)benzyl]carbamic acid tert-butyl ester
• CAS NO: 1253769-38-8
• Molecular Weight: 554.689
• Mol File: 1253769-38-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-ethyl-[4-(([6-(N-ethyl-N-methyl-carbamoyl)-2-oxo-1,2-dihydro-indol-3-ylidene]phenylmethyl)amino)benzyl]carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-ethyl-[4-(([6-(N-ethyl-N-methyl-carbamoyl)-2-oxo-1,2-dihydro-indol-3-ylidene]phenylmethyl)amino)benzyl]carbamic acid tert-butyl ester(1253769-38-8)
• EPA Substance Registry System: (Z)-ethyl-[4-(([6-(N-ethyl-N-methyl-carbamoyl)-2-oxo-1,2-dihydro-indol-3-ylidene]phenylmethyl)amino)benzyl]carbamic acid tert-butyl ester(1253769-38-8)

Safety Data

• Hazardous Substances Data: 1253769-38-8(Hazardous Substances Data)

Upstream product

• 247085-22-9 (4-aminobenzyl)-N-ethylcarbamic acid tert-butyl ester 
• 1253768-93-2 (Z)-3-(hydroxy-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid N-methyl-N-ethylamide 

Downstream Products

• 1253769-50-4 (Z)-3-[(4-(ethylaminomethyl)phenylamino)phenylmethylene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid n-methyl-ethylamide trifluoroacetate 

Relevant articles and documents

Design, synthesis, and evaluation of indolinones as inhibitors of the transforming growth factor β receptor i (TGFβRI)

Inhibition of transforming growth factor β (TGFβ) type I receptor (Alk5) offers a novel approach for the treatment of fibrotic diseases and cancer. Indolinones substituted in position 6 were identified as a new chemotype inhibiting TGFβRI concomitant with