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1253798-65-0

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1253798-65-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1253798-65-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,3,7,9 and 8 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1253798-65:
(9*1)+(8*2)+(7*5)+(6*3)+(5*7)+(4*9)+(3*8)+(2*6)+(1*5)=190
190 % 10 = 0
So 1253798-65-0 is a valid CAS Registry Number.

1253798-65-0Upstream product

1253798-65-0Relevant articles and documents

SYNTHESIS OF TETRACYCLINES AND INTERMEDIATES THERETO

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Page/Page column 121/251-122/251, (2010/11/17)

The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The recent development of a modular synthesis of tetracycline analogs through a chiral enone intermediate has allowed for the efficient synthesis of novel tetracycline analogs never prepared before. The present invention provides more efficient routes for preparing the enone intermediate and allows for substituents at positions 4a, 5, 5a, and 12a of the tetracycline ring system.

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