1253857-74-7

Basic information

• Product Name: rac-N-(1-(3-chlorophenyl)-3-phenyl-2-propynyl)-2-methoxyaniline
• Synonyms: rac-N-(1-(3-chlorophenyl)-3-phenyl-2-propynyl)-2-methoxyaniline
• CAS NO: 1253857-74-7
• Molecular Weight: 347.844
• Mol File: 1253857-74-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: rac-N-(1-(3-chlorophenyl)-3-phenyl-2-propynyl)-2-methoxyaniline(CAS DataBase Reference)
• NIST Chemistry Reference: rac-N-(1-(3-chlorophenyl)-3-phenyl-2-propynyl)-2-methoxyaniline(1253857-74-7)
• EPA Substance Registry System: rac-N-(1-(3-chlorophenyl)-3-phenyl-2-propynyl)-2-methoxyaniline(1253857-74-7)

Safety Data

• Hazardous Substances Data: 1253857-74-7(Hazardous Substances Data)

Upstream product

• 20442-97-1 2-methoxylphenyl azide 
• 587-04-2 m-Chlorobenzaldehyde 
• 536-74-3 phenylacetylene 

Relevant articles and documents

A novel efficient method for synthesis of propargylamines via three-component coupling of aryl azide, aldehyde, and alkyne promoted by iron-iodine-copper(I) bromide

A novel, efficient method has been developed for the synthesis of propargylamines through a three-component coupling of aryl azides, aldehydes, and alkynes in the presence of iron-iodine-copper(I) bromide as catalyst. This method is the first example for directly using aryl azides as an amino component in a three-component coupling reaction. Some of the major advantages of this protocol are: good yields, the involvement of a less-expensive and non-toxic catalyst, mild reaction conditions, and a wide range of substrates.